Annals of Indian Academy of Neurology
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Year : 2003  |  Volume : 6  |  Issue : 1  |  Page : 13-15

Familial Autoimmune Myasthenia Gravis (Report Of 3 Cases)



Correspondence Address:
A. S Girija


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Source of Support: None, Conflict of Interest: None


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Familial Autoimmune myasthenia gravis is rare, occurring in only about 1.3% cases of myasthenia gravis (MG). Here in we report a family with three family members affected by MG. Proband presented with generalised myasthenia where as the other two affected family members had only ocular myasthenia. Anti-acetylcholinereceptor antibody was strongly positive in the proband and he responded to steroids. His brother in addition had vitiligo over his face substantiating the autoimmune nature of myasthenia gravis. Familial cases of myasthenia gravis should be investigated with acetyl choline receptor antibody estimation and an attempt should be made to search for other autoimmune diseases in the patient and relatives.


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