Annals of Indian Academy of Neurology
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Year : 2004  |  Volume : 7  |  Issue : 2  |  Page : 369-374

Factors Influencing Anti Epileptic Drug Non-Compliance



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M Dhanaraj


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Non-compliances to anti epileptic drug therapy is one of the commonest causes of relapse of seizure. The various factors influencing non-compliance in a state government hospital where patients below poverty line are issued free drugs once in 2 weeks are unknown. In this study, 200 adult epilepsy patients consisting 100 complaint and non- complaint in each group were interviewed with a structured questionnaire. The relevant demographic and clinical characteristics such as awareness of altitude towards purchasing the drugs were collected. The data was analyzed using student "t" test and chi square test. The factors influencing non-compliance were, a)difficulty in collecting the drugs once in 2 weeks from the hospital (45% vs. 21%:p value < 0.001), b) Lack of family supported (42%vs.29%:p value < 0.05), c) Mental adverse effects of the drugs (54%vs.33%: value <0.002) and d) Poor motivation. The attitude of the patients was negative towards purchasing drugs even at times of emergency (84% vs. 44%:p value <0.001). Measures to rectify the above factors are suggested.


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