Annals of Indian Academy of Neurology
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REVIEW ARTICLE
Year : 2006  |  Volume : 9  |  Issue : 3  |  Page : 145-151

Coronary artery bypass surgery: Does it lead to cognitive impairment?


Department of Neurology, Sanjay Gandhi PGIMS, Lucknow, India

Correspondence Address:
U K Misra
Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow - 226 014
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.27656

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Coronary artery bypass grafting is an important treatment option for coronary artery disease. A wide variety of neurocognitive impairment ranging from stroke, postoperative delirium, depression and early and delayed impairment in memory and visuospatial functions has been reported. The results of the studies are variable because of various patient populations, associate comorbidity, timing of study and absence or type of controls. The reported causes of cognitive impairment are micro-emboli, hypo-perfusion, systemic inflammatory response syndrome, anesthesia, associated depression, genetic susceptibility and associated cardiovascular risk factor and MRI abnormalities. Further studies are needed to evaluate employing objective clinical and electrodiagnostic measures.


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