Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2010  |  Volume : 13  |  Issue : 1  |  Page : 69-71

Alpha coma evolving into spindle coma in a case of acute fulminant hepatic failure: What does it signify?


Department of Neurology, Sree Chitra Tirunal Institute of Medical Sciences and Technology, Trivandrum, India

Correspondence Address:
Ashalatha Radhakrishnan
Consultant in Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum-695 011, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.61285

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A 44-year-old male developed acute fulminant hepatic failure of unknown etiology and expired within four days. His serial electroencephalograms (EEGs) showed diffuse background slowing on day one, which evolved into "alpha coma" and later into "spindle coma" over the ensuing two days. Such EEG transition is hitherto undescribed in patients with hepatic encephalopathy and gives fresh insight into the etiopathogenesis of specific EEG patterns in diffuse encephalopathy.


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