Annals of Indian Academy of Neurology
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IMAGES IN NEUROLOGY
Year : 2010  |  Volume : 13  |  Issue : 3  |  Page : 221-222

Acute dengue myositis with rhabdomyolysis and acute renal failure


1 Department of Medicine, J.N Medical College, DMIMS University, Sawangi (Meghe), Wardha - 442 004, Maharashtra, India
2 Department of Pathology, J.N Medical College, DMIMS University, Sawangi (Meghe), Wardha - 442 004, Maharashtra, India

Correspondence Address:
Sourya Acharya
Department of Medicine, JNMC/DMIMSU, Sawangi (Meghe), Wardha - 442 004, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.70882

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Dengue is an acute mosquito-borne infection caused by dengue viruses from the genus flavivirus. Neurologic complications have been attributed chiefly to metabolic alterations and to focal and sometimes massive intracranial haemorrhages, but anecdotal cases and limited case series have indicated the possibility of viral CNS and skeletal muscle invasion causing encephalitis and myositis. We present a case of a 40-year-old male who presented with severe dengue myositis resulting in quadriparesis, respiratory failure and acute renal failure with red urine. His elevated serum creatine kinase (CK), serum and urine myoglobin levels justified rhabdomyolysis as the cause of acute renal failure. A muscle biopsy revealed inflammatory myositis. He required ventilator support for respiratory failure and was treated conservatively. This case highlights the severe and persistent muscle involvement in dengue which is a rarity.


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