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LETTER TO THE EDITOR
Year : 2012  |  Volume : 15  |  Issue : 3  |  Page : 234-235
 

Why need for five anti-tubercular drugs in a child with CNS TB?


Department of Pediatrics, SDM Medical College and Hospital, Dharwad, Karnataka, India

Date of Web Publication14-Aug-2012

Correspondence Address:
Praveen S Bagalkot
Pediatrics Department, SDM Medical College and Hospital, Dharwad- 580 009, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.99741

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How to cite this article:
Bagalkot PS. Why need for five anti-tubercular drugs in a child with CNS TB?. Ann Indian Acad Neurol 2012;15:234-5

How to cite this URL:
Bagalkot PS. Why need for five anti-tubercular drugs in a child with CNS TB?. Ann Indian Acad Neurol [serial online] 2012 [cited 2019 Oct 14];15:234-5. Available from: http://www.annalsofian.org/text.asp?2012/15/3/234/99741


Sir,

It was interesting to read a case report of Tuberculosis brain abscess and subdural empyema in an immune-competent child: Significance of AFB staining in aspirated pus by B Vijaykumar et al. [1] The treatment of childhood CNS tuberculosis is by four drugs (isoniazid, rifampicin, pyrazinamide, and ethambutol or streptomysin) along with steroids as per the Working Group on Tuberculosis, Indian Academy of Paediatrics. Consensus statement on childhood tuberculosis 2010. [2] It was not clear why did the authors used five anti-tubercular drugs in the management the case in the report. Rajneti Prasad et al, reported the use of four drugs (isoniazid, rifampicin, pyrazinamide, and ethambutol) in a child with tubercular abscess of Pons with quadriparesis. [3] Furthermore the need of evaluating the child in the case report for T cell immune-deficiency is not stressed and child needs follow up for neurological deficits and other symptoms before we assume the child is a immune-competent.

 
   References Top

1.Vijayakumar B, Sarin K, Mohan G. Tuberculous brain abscess and subdural empyema in an immune-competent child: Significance of AFB staining in aspirated pus. Ann Indian Acad Neurol 2012;15:130-3.  Back to cited text no. 1
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2.Working Group on Tuberculosis, Indian Academy of Paediatrics. Consensus statement on childhood tuberculosis, 2008. Indian Pediatr 2010;47:41-55.  Back to cited text no. 2
    
3.Prasad R, Bagri NK, Bagri N, Singh UK, Mishra OP. Tubercular abscess of pons in achild with quadriparesis. BMJ Case Rep 2010;2010. pii: bcr10.2009.2370. Epub 2010 Mar 17.  Back to cited text no. 3
    




 

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