Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2013  |  Volume : 16  |  Issue : 3  |  Page : 443-446

Spectroscopic correlation and role of Azathioprine in long-term remission in patients of Hashimoto encephalopathy


1 Department of Medicine, Pt. B.D.S. PGIMS, Rohtak, Haryana, India
2 Department of Radiology, Pt. B.D.S. PGIMS, Rohtak, Haryana, India

Correspondence Address:
Harpreet Singh
881/23, DLF Colony, Rohtak, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.116936

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Hashimoto encephalopathy remains a Rubik's cube for the present generation of clinical research. Myriad presentations have been noted, and observations recorded in few subgroups of patients have gone on only to be trashed by a second group of patients with a completely different clinical profile. Steroids have been traditionally held to be the treatment for this condition, but long-term side effects associated with it limits its use. Although multiple drugs have been tried, yet there exists no data for their long-term efficacy in maintaining remission. No radiological findings have been consistently associated with this condition. We report the use of azathioprine in maintaining long-term remission in one such patient with Hashimoto encephalopathy and the presence of lactate peak in magnetic resonance spectroscopy of the patient, which showed dramatic regression with institution of immunosuppression.


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