Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2014  |  Volume : 17  |  Issue : 1  |  Page : 108-112

Acanthamoeba meningoencephalitis


1 Professor of Neurology, Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka, India
2 Senior Resident Neurology, Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka, India
3 Additional Professor Neuropathology, Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka, India

Correspondence Address:
S R Chandra
Department of Neurology, Faculty Block, Neuro Centre, National Institute of Mental Health and Neuro Sciences, Bangalore - 560 029, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.128571

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Report of a case of young immunocompetent male adult with autopsy proven acanthamoeba meningoencephalitis. The patient presented with a protracted febrile illness of 3 months duration with features of meningoencephalitis, this was followed by rapid deterioration while on anti tuberculous therapy and steroids and ended fatally. His magnetic resonance imaging showed features of hemorrhagic meningoencephalitis and magnetic resonance spectroscopy showed choline peak. Autopsy revealed necrotizing meningoencephalitis and intraocular colonization due to acanthamoeba.


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