Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2014  |  Volume : 17  |  Issue : 1  |  Page : 123-124

Glutamate-based magnetic resonance spectroscopy in neuroleptic malignant syndrome


Department of Medicine, Nil Ratan Sircar Medical College, Kolkata, West Bengal, India

Correspondence Address:
Atri Chatterjee
Rajdeep Apartments, 18/1E, D. P. P. Road, Kolkata - 700 047, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.128579

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Glutamate neurotoxicity is implicated in a number of neurological diseases, including Neuroleptic Malignant syndrome. Therefore, functional magnetic resonance imaging can help in diagnosis and monitoring such conditions. However, reports of this application are scarce in the literature. In this manuscript, glutamate based imaging of the basal ganglia showed increased levels of the neurotransmitter bilaterally. In addition, a radon transform of the functional image was performed to look for any asymmetry in cerebral activation. Although no asymmetry was detected in this case, this novel analysis can be applied in physiological and pathological scenarios to visualize contribution of different brain structures.


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