Annals of Indian Academy of Neurology
  Users Online: 2806 Home | About the Journal | InstructionsCurrent Issue | Back IssuesLogin      Print this page Email this page  Small font size Default font size Increase font size
ORIGINAL ARTICLE
Year : 2014  |  Volume : 17  |  Issue : 3  |  Page : 267-271

Hippocampal volumetry: Normative data in the Indian population


Department of Neuro Imaging and Interventional Radiology, National Institute of Mental Health and Neuroscience, Banglore, Karnataka, India

Correspondence Address:
Rose Dawn Bharath
Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neuroscience, Dr M H Marigowda Road, Bangalore - 560 029, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.138482

Rights and Permissions

Background: Mesial temporal sclerosis (MTS) is the most common cause of temporal lobe epilepsy. Quantitative analysis of the hippocampus using volumetry is commonly being used in the diagnosis of MTS and is being used as a marker in prognostication of seizure control. Although normative data for hippocampal volume (HV) is available for the western population, no such data is available for the Indian population. Aim: The aim of the study was to establish normative data for HV for the Indian population, which can aid in the accurate diagnosis of MTS. Materials and Methods: Magnetic resonance imaging (MRI) scans of 200 healthy volunteers were acquired using a 3 Tesla (3T) MRI scanner. Manual segmentation and volumetry was done using Siemens Syngo software. The data was analyzed using two tailed t-test to detect associations between HV and age, gender, and education. The data so obtained was also correlated with the data available from the rest of the world. Results: A mean HV of 2.411 cm 3 (standard deviation -0.299) was found in the study, which was significantly smaller when compared to the data from the western population. The right hippocampus was larger than the left, with a mean volume of 2.424 cm 3 and 2.398 cm 3 , respectively. HV was detected to be significantly higher in males. No association was found between HV and age and education. Conclusion: The values obtained in this study may be adopted as a standard in the evaluation of patients with intractable epilepsy.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2488    
    Printed43    
    Emailed0    
    PDF Downloaded109    
    Comments [Add]    

Recommend this journal