Annals of Indian Academy of Neurology
  Users Online: 1300 Home | About the Journal | InstructionsCurrent Issue | Back IssuesLogin      Print this page Email this page  Small font size Default font size Increase font size


 
Table of Contents
LETTER TO THE EDITOR
Year : 2015  |  Volume : 18  |  Issue : 1  |  Page : 120-121
 

Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia


Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India

Date of Submission04-Jul-2014
Date of Decision28-Jul-2014
Date of Acceptance06-Aug-2014
Date of Web Publication10-Feb-2015

Correspondence Address:
Sunil Kumar Raina
Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra -176 001, Himachal Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.144315

Rights and Permissions

 



How to cite this article:
Raina SK. Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia. Ann Indian Acad Neurol 2015;18:120-1

How to cite this URL:
Raina SK. Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia. Ann Indian Acad Neurol [serial online] 2015 [cited 2019 Aug 25];18:120-1. Available from: http://www.annalsofian.org/text.asp?2015/18/1/120/144315


Sir,

Went through with interest an article entitled "Neuropsychiatric profiles in patients with Alzheimer's disease and vascular dementia" published in Ann Indian Acad Neurol (2014;17:325-30). [1] Given the fact that neuropsychiatric symptoms are common both in patients with Alzheimer disease (AD) and those with vascular dementia (VaD), [1] the study has highlighted an important issue and authors deserve credit for that. However, I have a few concerns with the methodology as described by the authors. The authors state that they used the mini-mental status exam (MMSE) for initial screening. They also used the Kolkata Cognitive Test Battery as also separately tested the language, praxis performance, executive functioning, as well as visuospatial and visuoperceptual functioning using standard methods. The authors claim that they based their diagnosis of dementia using Diagnostic and Statistical Manual of mental disorders. The authors further assessed behavioral and psychological symptoms on the basis of the NPI in the presence of a reliable caregiver. The authors translated the original NPI in to Bengali and used the same after following a standard technique.

Now this takes me to my concerns with this study. I am unable to understand the role of MMSE in this study. MMSE or its modifications have in past been used as a screening tool in a two phase surveys for assessment of dementia. [2],[3],[4] As a screening tool it has been used to pick suspects of dementia and further evaluation has been carried on suspects to confirm cases of dementia. Further a random sample of screen negatives is selected for second phase assessment. This does not seem to have been done in this study. If this was done, then what was the need of using MMSE as a screening tool? The study seems to have been conducted as a one-phase cross-sectional study after applying dementia criteria from Diagnostic and Statistical Manual of mental disorders (DSM-IV). Further, even if the authors have used MMSE for screening (as they claim), they have been unable to report on how MMSE was made culturally and linguistically sensitive to the population under study. It may not be appropriate to use MMSE (English language) in the study population. The authors seem to be aware of this and that is why they have translated and validated their study tool for assessment of behavioral and psychological symptoms. Should not the same be done with the screening tool for assessment of dementia?

 
   References Top

1.
Bandyopadhyay TK, Biswas A, Roy A, Guin DS, Gangopadhyay G, Sarkhel S, et al. Neuropsychiatric profiles in patients with Alzheimer′s disease and vascular dementia. Ann Indian Acad Neurol 2014;17:325-30.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Raina S, Razdan S, Pandita KK, Raina S. Prevalence of dementia among Kashmiri migrants. Ann Indian Acad Neurol 2008;11:106-8.  Back to cited text no. 2
[PUBMED]  Medknow Journal  
3.
Chandra, Ganguli M, Pandav R, Johnston J, Belle S, DeKosky ST. Prevalence of Alzheimer′s disease and other dementias in rural India: The Indo-US study. Neurology 1998;51:1000-8.  Back to cited text no. 3
    
4.
Raina SK, Raina S, Chander V, Grover A, Singh S, Bhardwaj A. Is dementia differentially distributed - A study on the prevalence of dementia in migrant, urban, rural and tribal elderly population of himalayan region in northern India. N Am J Med Sci 2014;6:172-7.  Back to cited text no. 4
    




 

Top
Print this article  Email this article

    

 
   Search
 
  
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (366 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  


    References

 Article Access Statistics
    Viewed1636    
    Printed20    
    Emailed0    
    PDF Downloaded55    
    Comments [Add]    

Recommend this journal