Annals of Indian Academy of Neurology
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Year : 2015  |  Volume : 18  |  Issue : 1  |  Page : 80-83

Bright splenium of a psychotic mind

Department of Neurology, Narayana Institute of Neurosciences, Narayana Health City, Bangalore, Karnataka, India

Correspondence Address:
Shankar C Udaya
Department of Neurosciences, Ground Floor, Mazumdar Shaw Medical Centre, Narayana Health City, Bommasandra Industrial Area, Hosur Main Road, Bangalore - 560 099, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.145287

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A twenty-one-year old primigravida presented two weeks postpartum with new onset of behavioral alteration and irrelevant talking without fever, headache, or seizures. Magnetic resonance imaging (MRI) of brain showed a lesion with diffusion restriction in splenium of corpus callosum. A possibility of postpartum psychosis was considered after ruling out various etiologies for splenium hyperintense lesion. Near complete resolution of symptoms was noted after initiation of antipsychotic medications. Literature has described multiple etiologies for lesions involving splenium of corpus callosum on brain imaging. We present this case as a unique clinical presentation of splenial pathology in the form of postpartum psychosis.

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