Annals of Indian Academy of Neurology
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CLINICAL SIGN
Year : 2015  |  Volume : 18  |  Issue : 2  |  Page : 154-156

Lhermitte's Sign: The Current Status


1 Armed Forces Medical College, Pune, India
2 Kasturba Medical College, Mangalore (Manipal University), India

Correspondence Address:
Supreet Khare
Armed Forces Medical College, Pune
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.150622

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Lhermitte's sign was described by Marie and Chatelin and named after Jean Lhermitte. This sign is mostly described as an electric shock like condition by some patients of multiple sclerosis. This sensation occurs when the neck is moved in a wrong way or rather flexed. It can also travel down to the spine, arms, and legs, and sometimes the trunk. Demyelination and hyperexcitability are the main pathophysiological reasons depicted for the Lhermitte's sign. Other causes for Lhermitte's sign include transverse myelitis, behηet's disease, trauma, etc. This article reviews the Lhermitte's sign, its history, and its etiopathophysiology. Very few studies are available on Lermitte's sign and more research need to be done on the same to ensure its sensitivity and specificity.


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