Annals of Indian Academy of Neurology
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CASE REPORT
Year : 2015  |  Volume : 18  |  Issue : 2  |  Page : 243-245

Limbic encephalitis with antibodies to glutamic acid decarboxylase presenting with brainstem symptoms


1 Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey
2 Department of Pediatric Intensive Care Unit, Cukurova University Faculty of Medicine, Adana, Turkey

Correspondence Address:
Faruk Incecik
Toros mah. 78186 sok. Ye?ilpark Evleri, Kat: 7, no: 13, Adana
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.150628

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Limbic encephalitis (LE) is a neurological syndrome that may present in association with cancer, infection, or as an isolate clinical condition often accompanying autoimmune disorders. LE associated with glutamic acid decarboxylase antibodies (anti-GAD) is rare in children. Here, we characterized the clinical and laboratory features of a patient presenting with brainstem involvement with non-paraneoplastic LE associated with anti-GAD antibodies. In our patient, after plasma exchange, we determined a dramatic improvement of the neurological deficits.


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