Annals of Indian Academy of Neurology
  Users Online: 2125 Home | About the Journal | InstructionsCurrent Issue | Back IssuesLogin      Print this page Email this page  Small font size Default font size Increase font size
CASE REPORT
Year : 2015  |  Volume : 18  |  Issue : 3  |  Page : 345-347

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): A case report and review of literature


1 Department of Neurosurgery, Apollo Health City, Jubilee Hills, Hyderabad, Andhra Pradesh, India
2 Department of Pathology, Apollo Health City, Jubilee Hills, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Rahul Lath
Department of Neurosurgery, Apollo Health City, Jubilee Hills, Hyderabad - 500 033, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-2327.152085

Rights and Permissions

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently described inflammatory disease of central nervous system with distinct clinical and radiological features. The etiopathogenesis of this rare entity remains to be understood. The histopathological findings closely resemble chronic inflammatory diseases like sarcoidosis and malignancies like lymphoma. With advancements in serology, immunopathology and radiology CLIPPERS is identified as a distinct entity that differs considerably in its clinical presentation, immunopathology, radiological findings and response to steroids. We describe a case that presented to us with progressive quadriparesis and lower cranial nerve deficits whose radiological and pathological findings were consistent with CLIPPERS. The patient had a good outcome with long term immunosuppression.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3158    
    Printed45    
    Emailed0    
    PDF Downloaded89    
    Comments [Add]    

Recommend this journal