Optical coherence tomography and subclinical optical neuritis in longitudinally extensive transverse myelitis

Prakash Kumar Sinha; Deepika Joshi; Virendra Pratap Singh; Sujit Deshmukh; Usha Singh; Abhishek Pathak; Vijay Nath Mishra; Rameshwar Nath Chaurasia; Vivek Sharda; Garima Gupta

doi:10.4103/aian.AIAN_170_17


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ORIGINAL ARTICLE

Year : 2017 | Volume : 20 | Issue : 4 | Page : 358-362

Optical coherence tomography and subclinical optical neuritis in longitudinally extensive transverse myelitis

Prakash Kumar Sinha¹, Deepika Joshi¹, Virendra Pratap Singh², Sujit Deshmukh², Usha Singh³, Abhishek Pathak¹, Vijay Nath Mishra¹, Rameshwar Nath Chaurasia¹, Vivek Sharda¹, Garima Gupta¹
¹ Department of Neurology, IMS, BHU, Varanasi, Uttar Pradesh, India
² Department of Ophthalmology, IMS, BHU, Varanasi, Uttar Pradesh, India
³ Department of Pathology, IMS, BHU, Varanasi, Uttar Pradesh, India

Correspondence Address:
Deepika Joshi
Department of Neurology, IMS, BHU, Varanasi - 221 005, Uttar Pradesh
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/aian.AIAN_170_17

Objective: The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects. Methods: Over 20 LETM eyes and 20 normal control eyes were included in the study and subjected to optical coherence tomography to evaluate and compare the RNFL thickness. Result: Significant RNFL thinning was observed at 8 o'clock position in LETM eyes as compared to the control eyes (P = 0.038). No significant differences were seen in other RNFL measurements. Conclusion: Even in the absence of previous optic neuritis LETM can lead to subclinical axonal damage leading to focal RNFL thinning.

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