Annals of Indian Academy of Neurology
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Year : 2018  |  Volume : 21  |  Issue : 4  |  Page : 311-314

Paraneoplastic cerebellar degeneration associated with ovarian adenocarcinoma: A case report and review of literature

1 Department of Neurosciences, Institute of Neurosciences, Indraprastha Apollo Hospitals, New Delhi, India
2 Department of Neurosciences, Institute of Neurosciences/Internal Medicine, Indraprastha Apollo Hospitals, New Delhi, India
3 Department of Internal Medicine, BHEL, Haridwar, Uttarakhand, India

Correspondence Address:
Dr. Pushpendra Nath Renjen
C-85, Anand Niketan, New Delhi - 110 021
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aian.AIAN_411_17

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Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabolic and nutritional deficits, or side effects of treatment. When tumor- and treatment-related causes have been excluded, the patient is considered to suffer from paraneoplastic cerebellar degeneration (PCD). We report a case of PCD that presented before any evidence of tumor, but early diagnostic workup and clinical vigilance helped us to find the underlying high-grade ovarian adenocarcinoma which was surgically removed later.

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