Annals of Indian Academy of Neurology
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Year : 2019  |  Volume : 22  |  Issue : 2  |  Page : 131-136

Can we treat secondary progressive multiple sclerosis now?


Department of Neurology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Rohit Bhatia
Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi - 110 029
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aian.AIAN_345_18

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Secondary progressive multiple sclerosis (SPMS) is characterized by progressive accumulation of disability without intermittent recovery. Treatment of these patients is challenging due to limited understanding of pathogenesis and fewer therapeutic options. This article summarizes difficulties in defining and conducting trials in SPMS, review major clinical trials on therapies approved and unapproved in SPMS and lastly, therapies in pipeline for use in SPMS.


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