Annals of Indian Academy of Neurology
  Users Online: 949 Home | About the Journal | InstructionsCurrent Issue | Back IssuesLogin      Print this page Email this page  Small font size Default font size Increase font size
ORIGINAL ARTICLE
Year : 2020  |  Volume : 23  |  Issue : 1  |  Page : 20-24

Apomorphine: The initial indian experience in relation to response tests and pumps


1 Center for Parkinson's Disease and Movement Disorders Clinic; Department of Neurology, Institute of Neurosciences, Vikram Hospitals; Parkinson's Disease and Movement Disorders Clinic, Bengaluru, Karnataka, India
2 Department of Neurology, Institute of Neurosciences, Vikram Hospitals, Bengaluru, Karnataka, India

Correspondence Address:
Dr. L K Prashanth
Center for Parkinson's Disease and Movement Disorders Clinic, Vikram Hospitals, Bangalore, Karnataka - 560 052
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aian.AIAN_428_19

Rights and Permissions

Background: Apomorphine is an option for continuous dopaminergic therapy in Parkinson's disease (PD). However, its effects in varied populations are limited due to its availability. Objective: To assess the efficacy and outcomes of apomorphine in Indian patients. Materials and Methods: Retrospective analysis of PD patients who underwent apomorphine response test (ART), along with the subset, who went on to apomorphine pumps. Results: Twenty-nine confirmed PD patients underwent ART and all PD patients showed good clinical response. 19 subjects developed adverse events which included: nausea (n-15, 51.7%), vomiting (n-10, 34.4%), sleepiness (n-08; 27.5%), yawning (n-07, 24.1%), postural hypotension (n-03, 10.3%), dizziness (n-03, 10.3%), and profuse sweating (n-01, 3.4%). Apomorphine pumps were initiated in six subjects, with significant clinical improvement. Adverse events on pump included subcutaneous nodules, nausea, hypersexuality. Two among them subsequently discontinued the pump primarily due to financial constraints. Conclusions: Apomorphine adds up to the armamentarium for treatment of PD patients in India with good clinical responses.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed332    
    Printed13    
    Emailed0    
    PDF Downloaded35    
    Comments [Add]    

Recommend this journal