Annals of Indian Academy of Neurology
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Year : 2020  |  Volume : 23  |  Issue : 2  |  Page : 225-227

Anti-N-methyl-D-aspartate receptor encephalitis: Case series of psychiatric presentations

1 Department of Psychiatry, Dr. S. N. Medical College, Jodhpur, Rajasthan, India
2 Department of Psychiatry, Subharti Medical College, Meerut, Uttar Pradesh, India

Correspondence Address:
Dr. Arpit Koolwal
27A/51, Light Industrial Area, Adarsh Society, Shastri Nagar, Jodhpur, Rajasthan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aian.AIAN_295_18

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Anti-NMDAR encephalitis is an autoimmune encephalitis with a typical clinical progression. Patients can often present to psychiatric outpatient departments (OPDs) mimicking psychiatric illnesses. In this case series, we have described two cases of adolescent age group that were eventually diagnosed with anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. They had presented to psychiatry OPD and were admitted to the psychiatry ward. Both cases had predominantly, although varied, psychiatric symptoms with a variable course, response to treatment and prognosis. We have tried to speculate if initial presentation in anti-NMDAR encephalitis can be suggestive or can predict response to treatment and prognosis in a patient. We advocate a high degree of suspicion for psychiatrists toward patients presenting acutely in the first episode of mania or psychosis, particularly in adolescent age group.

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