Annals of Indian Academy of Neurology
SHORT COMMUNICATION
Year
: 2007  |  Volume : 10  |  Issue : 2  |  Page : 105--108

Gelastic epilepsy associated with lesions other than hypothalamic hamartoma


Ashok Panagariya1, Bhawna Sharma1, Gautam Tripathi1, Hrisikesh Kumar2, Vinay Agarwal1 
1 Department of Neurology, SMS Medical College and Attached Hospitals, Jaipur, India
2 S. K. Soni Hospital, Jaipur, India

Correspondence Address:
Ashok Panagariya
7, Raj Niketan, Moti Doongri Road, Jaipur - 302 004
India

Gelastic epilepsy is a rare but well recognized epileptic syndrome typically manifesting in early childhood. It is characterized by recurrent brief seizures with initial laughter or grimacing. Also known as DQlaughingDQ seizures, their association with hypothalamic hamartomas is well known in children and adults; however other structural causes have also been implicated. This study reports three cases of gelastic seizures, one each of Tuberous sclerosis, Left temporal gliosis and Hypothalamic Hamartoma with neuronal migration defect respectively. Though these seizures are usually pharmacoresistant and may end up as a severe epileptic encephalopathy and catastrophic epilepsy of childhood, all of our cases responded well to antiepileptic medication (carbamazepine and valproate). This study underscores the fact that certain brain abnormalities other than hypothalamic tumors are also associated with gelastic seizures. The clinical characteristic of seizures in these patients is different than those of isolated hypothalamic hamartomas and that these seizures can be well controlled with antiepileptic drugs.


How to cite this article:
Panagariya A, Sharma B, Tripathi G, Kumar H, Agarwal V. Gelastic epilepsy associated with lesions other than hypothalamic hamartoma.Ann Indian Acad Neurol 2007;10:105-108


How to cite this URL:
Panagariya A, Sharma B, Tripathi G, Kumar H, Agarwal V. Gelastic epilepsy associated with lesions other than hypothalamic hamartoma. Ann Indian Acad Neurol [serial online] 2007 [cited 2020 Feb 25 ];10:105-108
Available from: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2007;volume=10;issue=2;spage=105;epage=108;aulast=Panagariya;type=0