Annals of Indian Academy of Neurology
ORIGINAL ARTICLE
Year
: 2008  |  Volume : 11  |  Issue : 1  |  Page : 37--40

Quality of life in Wilson«SQ»s disease


RN Komal Kumar1, AB Taly1, K.P.S Nair2, S Sinha1, LK Prashanth1, N Vidya1, GR Arunodaya1, S Rao3 
1 Department of Neurology, National Institute of Mental Health and NeuroSciences (NIMHANS), Bangalore, India
2 Department of Psychiatric and Neurological Rehabilitation, National Institute of Mental Health and NeuroSciences (NIMHANS), Bangalore, India
3 Department of Biostatistics, National Institute of Mental Health and NeuroSciences (NIMHANS), Bangalore, India

Correspondence Address:
A B Taly
Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore - 560 029
India

Background: Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. Aim: To correlate clinical severity and QoL in patients with Wilson«SQ»s disease (WD). Materials and Methods: We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. Results: All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other ( p < 0.01). The NSS correlated inversely with the physical domain ( p < 0.02), while the duration of treatment had a positive correlation with the physical domain ( p < 0.01). None of the other features of QoL showed any significant correlation with age, NSS or duration of treatment. Conclusion: QoL is complementary to formal neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders.


How to cite this article:
Komal Kumar R N, Taly A B, Nair K, Sinha S, Prashanth L K, Vidya N, Arunodaya G R, Rao S. Quality of life in Wilson's disease.Ann Indian Acad Neurol 2008;11:37-40


How to cite this URL:
Komal Kumar R N, Taly A B, Nair K, Sinha S, Prashanth L K, Vidya N, Arunodaya G R, Rao S. Quality of life in Wilson's disease. Ann Indian Acad Neurol [serial online] 2008 [cited 2019 Dec 10 ];11:37-40
Available from: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=Komal;type=0