Annals of Indian Academy of Neurology
CASE REPORT
Year
: 2008  |  Volume : 11  |  Issue : 2  |  Page : 114--115

Magnetic resonance imaging may simulate progressive multifocal leucoencephalopathy in a patient with chronic lymphocytic leukemia after fludarabine therapy


J Kalita, NS Patel, UK Misra 
 Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

Correspondence Address:
U K Misra
Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow - 226 014
India

A 60-year-old male with chronic lymphatic leukemia (CLL) after 6 months of fludarabine therapy was admitted with status epilepticus and developed left hemiplegia. His magnetic resonance imaging revealed multiple T2 hyperintense lesions in the right frontal and left parieto-occipital lesion, simulating progressive multifocal leucoencephalopathy (PML). Cerebrospinal fluid Polymerase Chain Reaction (PCR) for JC virus was negative. We suggest the possible role of fludarabine in producing PML-like lesions in patients with Chronic Lymphocytic Leukemia (CLL).


How to cite this article:
Kalita J, Patel N S, Misra U K. Magnetic resonance imaging may simulate progressive multifocal leucoencephalopathy in a patient with chronic lymphocytic leukemia after fludarabine therapy.Ann Indian Acad Neurol 2008;11:114-115


How to cite this URL:
Kalita J, Patel N S, Misra U K. Magnetic resonance imaging may simulate progressive multifocal leucoencephalopathy in a patient with chronic lymphocytic leukemia after fludarabine therapy. Ann Indian Acad Neurol [serial online] 2008 [cited 2019 Dec 10 ];11:114-115
Available from: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=2;spage=114;epage=115;aulast=Kalita;type=0