Annals of Indian Academy of Neurology
ORIGINAL ARTICLE
Year
: 2015  |  Volume : 18  |  Issue : 2  |  Page : 177--180

Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India


Ravikesh Tripathi1, Keshav Kumar2, Rakesh Balachandar3, P Marimuthu4, Mathew Varghese3, Srikala Bharath3 
1 Department of Psychology, Narayana Health, Mazumdar Shaw Medical Centre, Bangalore, India
2 Department of Clinical Psychology, NIMHANS, Bangalore, Karnataka, India
3 Department of Psychiatry, NIMHANS, Bangalore, Karnataka, India
4 Department of Biostatistics and Psychiatry, NIMHANS, Bangalore, Karnataka, India

Correspondence Address:
Srikala Bharath
Professor of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore, Karnataka
India

Background: Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia. Persons with MCI are at higher risk to develop dementia. Identifying MCI from normal aging has become a priority area of research. Neuropsychological assessment could help to identify these high risk individuals. Objective: To examine clinical utility and diagnostic accuracy of neuropsychological measures in identifying MCI. Materials and Methods: This is a cross-sectional study of 42 participants (22 patients with MCI and 20 normal controls [NC]) between the age of 60 and 80 years. All participants were screened for dementia and later a detailed neuropsychological assessment was carried out. Results: Persons with MCI performed significantly poorer than NC on word list (immediate and delayed recall), story recall test, stick construction delayed recall, fluency and Go/No-Go test. Measures of episodic memory especially word list delayed recall had the highest discriminating power compared with measures of semantic memory and executive functioning. Conclusion: Word list learning with delayed recall component is a possible candidate for detecting MCI from normal aging.


How to cite this article:
Tripathi R, Kumar K, Balachandar R, Marimuthu P, Varghese M, Bharath S. Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India.Ann Indian Acad Neurol 2015;18:177-180


How to cite this URL:
Tripathi R, Kumar K, Balachandar R, Marimuthu P, Varghese M, Bharath S. Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India. Ann Indian Acad Neurol [serial online] 2015 [cited 2020 Sep 18 ];18:177-180
Available from: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=2;spage=177;epage=180;aulast=Tripathi;type=0