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Figure 3: (a and c) Superfi cial cortical, penetrating arterioles with rigid round profi les and amorphous eosinophilic amyloid deposits in the vessel walls which are congophilic and birefringent (c). (b) An amyloid senile plaque (arrow) as seen in a hematoxylin and eosin stained section. It demonstrates Maltese cross birefringence with Congo red (c, arrow). (d) Beta-amyloid staining labels the vessels (arrow), the diffuse amyloid plaque (open arrow), and the cored mature plaque (arrowhead) (a and b: H and E stain; c: Congo-red stain; d: betaamyloid immunostaining; original magnifi cation, a and c: ×160, b: ×320, d: ×80).

Figure 3: (a and c) Superfi cial cortical, penetrating arterioles with rigid round profi les and amorphous eosinophilic amyloid deposits in the vessel walls which are congophilic and birefringent (c). (b) An amyloid senile plaque (arrow) as seen in a hematoxylin and eosin stained section. It demonstrates Maltese cross birefringence with Congo red (c, arrow). (d) Beta-amyloid staining labels the vessels (arrow), the diffuse amyloid plaque (open arrow), and the cored mature plaque (arrowhead) (a and b: H and E stain; c: Congo-red stain; d: betaamyloid immunostaining; original magnifi cation, a and c: ×160, b: ×320, d: ×80).