Indian J Med Microbiol Close
 

Figure 1: (a) Section from the hippocampus reveals numerous intracytoplasmic eosinophillic Negri bodies within the cytoplasm of Ammon's horn neurons (arrows, a). Abundant rabies viral antigen is seen accumulating within the cytoplasm of the neurons on immunostaining (inset a, arrow). (b) Rabies viral nucleocapsid antigen is also seen accumulating as variably sized rounded deposits within the Purkinje neurons of the cerebellum (arrows), corresponding to Negri bodies, with spread along the apical dendrites into the overlying molecular layer (a: HE ×200, inset: Immunoperoxidase ×200; b: Immunoperoxidase ×200)

Figure 1: (a) Section from the hippocampus reveals numerous intracytoplasmic eosinophillic Negri bodies within the cytoplasm of Ammon's horn neurons (arrows, a). Abundant rabies viral antigen is seen accumulating within the cytoplasm of the neurons on immunostaining (inset a, arrow). (b) Rabies viral nucleocapsid antigen is also seen accumulating as variably sized rounded deposits within the Purkinje neurons of the cerebellum (arrows), corresponding to Negri bodies, with spread along the apical dendrites into the overlying molecular layer (a: HE ×200, inset: Immunoperoxidase ×200; b: Immunoperoxidase ×200)