Indian J Med Microbiol Close
 

Figure 1: Natural nucleotide and some chemical backbone modifications in synthetic nucleotides. NNt, natural nucleotide; PS, Phosphorothioate; NP, N3'-P5' Phosphoroamidate; OMe, 2'-O-methyl; MOE, 2'-O-methoxy-ethyl; LNA, locked nucleic acid; PMO, phosphoroamidate morpholino

Figure 1: Natural nucleotide and some chemical backbone modifications in synthetic nucleotides. NNt, natural nucleotide; PS, Phosphorothioate; NP, N3'-P5' Phosphoroamidate; OMe, 2'-O-methyl; MOE, 2'-O-methoxy-ethyl; LNA, locked nucleic acid; PMO, phosphoroamidate morpholino