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Figure 2: Exon-skipping eteplirsen ASO recognizes DMD exon 51 in pre-mRNA and converts out-of-frame into in-frame smaller transcript of dystrophin. DMD, Duchenne muscular dystrophy; mRNA, messenger RNA; ASO, antisense oligonucleotide

Figure 2: Exon-skipping eteplirsen ASO recognizes DMD exon 51 in pre-mRNA and converts out-of-frame into in-frame smaller transcript of dystrophin. DMD, Duchenne muscular dystrophy; mRNA, messenger RNA; ASO, antisense oligonucleotide