Annals of Indian Academy of Neurology
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Year : 2007  |  Volume : 10  |  Issue : 2  |  Page : 115-117

Extramedullary haematopoiesis causing spinal cord compression: A rare presentation with excellent outcome

Department of Radiation Oncology, Tata Memorial Hospital, Mumbai - 400012, India

Correspondence Address:
Siddhartha Laskar
Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai - 400 012
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.33221

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Extramedullary haematopoiesis (EMH) as a cause of spinal cord compression in patients with thalassaemia major is very rare. Treatment of EMH includes the use of radiotherapy, hypertransfusion, laminectomy and chemotherapy in the form of hydroxyurea We report a presentation of progressive paraparesis due to a sacral mass in a 7 year old child undergoing repeated blood transfusions for thalassaemia major who had a dramatic improvement in symptoms after radiotherapy. A standard recommendation regarding the radiation dose required is not available but a dose of 20Gy delivered over 10 fractions seems to be effective and well tolerated.

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