Annals of Indian Academy of Neurology
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Year : 2013  |  Volume : 16  |  Issue : 2  |  Page : 264-265

Vogt-Koyanagi-Harada syndrome presenting with encephalopathy

1 Department of Infectious and Tropical Diseases, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Alireza E Naeini
Shams Abadi St. No.106, Razi Medical building, 8134776514, Isfahan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.112490

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VogtKoyanagi-Harada (VKH) is a rare syndrome affecting tissues with melanocytes. The possibility that VKH syndrome has an autoimmune pathogenesis is supported by the high frequency of human leukocyte antigen-DR4 commonly associated with other autoimmune diseases. Eyes are the main affected organ, resulting in blindness. Brain disease as a late onset event is extremely rare. Here, we are reporting a 57-year-old woman with previously diagnosed VKH syndrome, presenting with a late-onset brain encephalopathy. She was treated with corticosteroids and discharged from hospital with good general condition.

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