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Year : 2014  |  Volume : 17  |  Issue : 1  |  Page : 142

A rare presentation of methanol toxicity

Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India

Date of Web Publication12-Mar-2014

Correspondence Address:
Nikhil Gupta
Department of Medicine, Guru Tegh Bahadur Hospital, Shahdara, New Delhi - 110 095
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-2327.128598

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How to cite this article:
Gupta N, Sonambekar AA, Daksh SK, Tomar L. A rare presentation of methanol toxicity. Ann Indian Acad Neurol 2014;17:142

How to cite this URL:
Gupta N, Sonambekar AA, Daksh SK, Tomar L. A rare presentation of methanol toxicity. Ann Indian Acad Neurol [serial online] 2014 [cited 2021 Sep 19];17:142. Available from:

Dear Sir,

I am glad that people are reading my article and raising queries on it. This is a mean of healthy interaction that can be carried out.

In our manuscript, the magnetic resonance imaging (MRI) of the brain had hemorrhagic conversion of infarct in bilateral parasagittal, parietooccipital region. An acute infarct was seen in right cerebellum. There were punctate infarcts in bilateral frontal regions.

These findings have been shown in the figure attached it the manuscript. I would like to point out that information given by Taheri et al., is quite different from those given our manuscript. Our patient had hemorrhagic conversion of infarct, which has not been described by Taheri et al. [1] Also, infarct in frontal lobe in case of methanol poisoning has been described Ashan et al., only [2] as per the PubMed search.

Sefidbakht et al., [3] described bilateral necrosis of the basal ganglia along with other brain lesions as described include edema, necrosis of subcortical white and gray matter, cerebellar cortical lesions, subarachnoid hemorrhage, bilateral intracerebral hemorrhage, and diffuse cerebral edema. Again, there is not any mention of the areas and nature of lesions on MRI found in our case report.

The lesions described by our case report were a combined mixture of the lesions that have been described in different case series and reports. Hemorrhagic conversion in case of infarcts in methanol poisoning has not been described. Last, frontal infarcts in methanol poisoning have been described in only one case report as mentioned above.

   References Top

1.Taheri MS, Moghaddam HH, Moharamzad Y, Dadgari S, Nahvi V. The value of brain CT findings in acute methanol toxicity. Eur J Radiol 2010;73:211-4.  Back to cited text no. 1
2.Ahsan H, Akbar M, Hameed A. Diffusion weighted image findings in methanol intoxication. J Pak Med Assoc 2009;59:321-3.  Back to cited text no. 2
3.Sefidbakht S, Rasekhi AR, Kamali K, Borhani Haghighi A, Salooti A, Meshksar A, et al. Methanol poisoning: Acute MR and CT findings in nine patients. Neuroradiology 2007;49:427-35.  Back to cited text no. 3


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