Annals of Indian Academy of Neurology
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Year : 2014  |  Volume : 17  |  Issue : 1  |  Page : 145

Clinical practice of multiple sclerosis

PD Hinduja National Hospital, Mahim, Mumbai, Maharashtra, India

Date of Web Publication12-Mar-2014

Correspondence Address:
Roop D Gursahani
PD Hinduja National Hospital, Mahim, Mumbai, Maharashtra
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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Gursahani RD. Clinical practice of multiple sclerosis. Ann Indian Acad Neurol 2014;17:145

How to cite this URL:
Gursahani RD. Clinical practice of multiple sclerosis. Ann Indian Acad Neurol [serial online] 2014 [cited 2021 Apr 12];17:145. Available from:

M. V. Padma Srivastava, Rohit Bhatia
Year of Publication: 2014, pp. 250
Publisher: Kontentworx, India

This slim volume has been midwifed by two of the current All India Institute of Medical Sciences Neurology faculty, one of whom (RB) has a subspeciality interest in neuroimmunology. They have involved a diverse set of authors from all parts of India. Their obvious aim is to produce an accessible book on all aspects of MS for Indian neurologists.

The first part of the book deals with various aspects of diagnosis. Magnetic resonance imaging is the mainstay of diagnosis and is well covered in the chapter on imaging. The subsequent chapter on lab diagnosis discusses both cerebrospinal fluid oligoclonal bands and optical coherence tomography in some detail but there is no mention of evoked potentials. This is followed by the diagnostic criteria. An elaborate explanation of the McDonald system is preceded by a less relevant detailed exposition on the evolution of the diagnostic criteria. Differential diagnosis is dispatched in a rather short chapter. For instance I could find no mention of Susac's syndrome.

An excellent review of neuromyelitis optica is followed by a couple of comprehensive and well written chapters on therapies for relapsing-remitting multiple sclerosis. The trial data are carefully tabulated with short descriptions of all the currently used disease modifying therapies. What is missing is a clear statement on how to make a choice between available disease modifying treatments as also how to treat patients who cannot afford any of the standard agents. The last section of the book deals with progressive MS and has very useful chapters on symptomatic treatment. Unfortunately there is no index.

Those of us who have a significant interest in the care of patients with MS will find this a very useful book to have available in the clinic for ready reference.


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