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Figure 1b: 26 year male presented with acute onset paraparesis, retention of urine, and disorientation. One month earlier he had right focal motor seizures with transient post ictal weakness for which he had been investigated elsewhere with no details. MRI brain [Figure 1A] on T2W images showed large hyperintense lesions in the temporal and parietal subcortex on the right side with scattered small hyperintense lesions predominantly in subcortical white matter of the opposite hemisphere. MRI of the spinal cord [Figure 1B] on T2W images showed liner hyperintense lesion in the dorsal cord which enhanced moderately following intravenous contrast. He was HIV positive and succumbed shortly thereafter.Autopsy of the brain lesion confirmed the clinical diagnosis of progressive multifocal leucoencephalopathy

Figure 1b: 26 year male presented with acute onset paraparesis, retention of urine, and disorientation. One month earlier he had right focal motor seizures with transient post ictal weakness for which he had been investigated elsewhere with no details. MRI brain [Figure 1A] on T2W images showed large hyperintense
lesions in the temporal and parietal subcortex on the right side with scattered small hyperintense lesions predominantly in subcortical white matter of the opposite hemisphere. MRI of the spinal cord [Figure 1B] on T2W images showed liner hyperintense lesion in the dorsal cord which enhanced moderately following
intravenous contrast. He was HIV positive and succumbed shortly thereafter.Autopsy of the brain lesion confirmed the clinical diagnosis of progressive multifocal leucoencephalopathy